
{"id":2852,"date":"2024-10-23T12:16:34","date_gmt":"2024-10-23T11:16:34","guid":{"rendered":"https:\/\/oximio.com\/?post_type=oximio-resources&#038;p=2852"},"modified":"2024-11-13T13:32:17","modified_gmt":"2024-11-13T12:32:17","slug":"israel-a-modern-beacon-for-clinical-trials-innovation","status":"publish","type":"oximio-resources","link":"https:\/\/oximio.com\/resources\/israel-a-modern-beacon-for-clinical-trials-innovation\/","title":{"rendered":"Israel: A Modern Beacon for Clinical Trials Innovation\u00a0"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2852\" class=\"elementor elementor-2852\">\n\t\t\t\t<section class=\"elementor-element elementor-element-17da83a6 e-con-full e-flex e-con e-parent\" data-id=\"17da83a6\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-71abf4b0 e-flex e-con-boxed e-con e-child\" data-id=\"71abf4b0\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-284e0d75 elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"284e0d75\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-2853 size-full\" src=\"https:\/\/oximio.com\/wp-content\/uploads\/2024\/10\/Israel-clinical-trials-logistics.jpg\" alt=\"Clinical trial services Israel: Innovation and News\" width=\"705\" height=\"591\" srcset=\"https:\/\/oximio.com\/wp-content\/uploads\/2024\/10\/Israel-clinical-trials-logistics.jpg 705w, https:\/\/oximio.com\/wp-content\/uploads\/2024\/10\/Israel-clinical-trials-logistics-300x251.jpg 300w\" sizes=\"(max-width: 705px) 100vw, 705px\" \/><\/p><p><span data-contrast=\"auto\">Israel\u2019s dynamic blend of cutting-edge medical innovation, world-class research institutions, and a supportive regulatory environment makes it an increasingly attractive destination for conducting clinical trials that hold the promise of breakthrough discoveries in healthcare.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">In this Insight we look at the clinical trials landscape within the country and why it is a compelling destination for clinical research.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><h2><span data-contrast=\"auto\">Clinical Trials Environment<\/span>\u00a0<\/h2><p><span data-contrast=\"auto\">According to, ClinicalTrials.gov there have been more than 1,766 clinical trials in Israel since 2020. The country has attracted pharmaceutical companies from around the globe wishing to carry out clinical trials. Up until 2022, clinical trials averaged 300 studies per year. This figure temporarily reduced in 2021 due to Covid19 restrictions. However, since the start of 2022, a further 278 trials have been registered and it is anticipated that by 2023, clinical trial numbers will have returned to previous levels.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">According to Global Data, Israel\u2019s healthcare market analysis showed that the Israel pharmaceutical industry was valued at $2.4 bn in 2018. This is expected to increase further by 2027. Key drivers of this market are a strong network of academic and research institutions R&amp;D facilities and developed medical facilities.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">There are currently 1,800 operational life sciences companies in Israel. These are divided into four main sectors: Telemedicine, Medical Devices, Biotechnology and Pharmaceutical therapies. In Q2 2022, a study by Longevity Israel showed that oncology was responsible for the majority of clinical trials within the country at that time (650+). This was followed by cardiology (132+), gastroenterology (130+) and kidney treatments (110). Over 100 clinical trials are researching infectious disease, with almost 30% of these devoted to Covid19. Another area of important research was women\u2019s health and there were approximately 90 studies looking at infertility, labour, and pre-eclampsia.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">A study by Longevity Israel, shows that Tel Aviv has the largest number of research and development hubs, BioTech companies and clinics and hospitals running clinical trials.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">In 2021, the Medical Device sector accounted for approximately 36% of R&amp;D companies whilst Telemedicine was the second largest sub-sector, experiencing a 3% increase in representation in life science companies in 2020. This makes it the fastest growing sub sector. BioTech and Pharmaceutical businesses remained consistent in 2020. Looking ahead to 2022, the distribution of sub-sectors remains unchanged from 2021 during the first 9 months of the year.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><h2><span data-contrast=\"auto\">Government Incentives and Favourable Regulatory Support<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">In a bid to encourage sponsors to conduct their clinical trials in the country, the Government offers grants, funding and tax incentives to new business investors in addition to providing a favourable regulatory environment for the running of trials. For example, all IMPs require licences but most of the exported drugs do not require an export licence. The Government\u2019s favourable incentives have resulted in cost advantages compared to Europe, US and some Asian countries. Advanced Tech Industries Group advises that approximately 66% of the total life science companies are less than a decade old attracted by Government incentives. The Government has designated national priority areas and development zones in peripheral areas to help stimulate economic growth, incentivising entrepreneurs to establish businesses within these regions. The MoH has also gone as far as to set-up a dedicated, centralised database of clinical studies conducted within the country, making readily available the latest information on clinical research activities.\u00a0<\/span>\u00a0<br \/><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><h2><span data-contrast=\"auto\">Population<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">With a population of over 9.5 million people, Israel benefits from a diverse patient pool. The population is insured through national health insurance and the medical history of individuals is easily tracked over time. This means that the Israeli healthcare system offers significant advantages in the long-term monitoring of participants.<\/span>\u00a0<\/p><h2><span data-contrast=\"auto\">Geography<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">Situated in the Middle East on the Mediterranean Sea, Israel has excellent airport connections. Combined with a small geographical footprint and extensive road networks, transportation within the country is smooth enabling quick access to clinical trial sites.\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><h2><span data-contrast=\"auto\">Opportunities<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2><p><strong>Artificial Intelligence (AI)\u00a0<\/strong><\/p><p><span data-contrast=\"auto\">The rapid evolution of AI has brought about significant transformations across multiple industries, not least of which is the healthcare industry which has seen significant advancements with the promise of even more remarkable progress in the years to come. These upcoming innovations hold the potential to significantly improve healthcare for billions of people worldwide. Machine learning is opening up new possibilities for discoveries across a variety of areas including early disease detection via imaging and diagnostics in breast cancer and diabetic retinopathy screening. There are also opportunities, with the benefits of genomics, for personalised healthcare.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Researchers, technology giants and traditional pharmaceutical establishments, are all investing in the potential solutions of cutting-edge AI with a view to providing improved patient access and care to patients.\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">According to\u00a0<span class=\"TextRun SCXW85540247 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW85540247 BCX0\">Tracxn (<\/span><\/span><span class=\"TextRun SCXW85540247 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun Superscript SCXW85540247 BCX0\" data-fontsize=\"11\">1)<\/span><\/span><span class=\"TextRun SCXW85540247 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW85540247 BCX0\">,<\/span><\/span><\/span><span data-contrast=\"auto\">\u00a0as of April 2023, there are 211 AI healthcare startups in Israel. Of, these 106 are based in Tel Aviv.\u00a0 Some of the most diverse research includes: home based urine analysis using smartphone; AI-based eyewear attachment with features to improve text reading, face recognition, colour identification and more and an AI-based social robot that acts as a companion for the elderly.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><strong>Medical Cannabis\u00a0<\/strong><\/p><p><span data-contrast=\"auto\">Israel is considered a global leader in the field of medical cannabis research and innovation. Backed by a pro-active Government, it has attracted research organisations from across the world, keen to take advantage of the Ministry of Health\u2019s sponsorship of cannabis research, and regulatory acquiescence.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><h2><span data-contrast=\"auto\">Oximio&#8217;s Clinical Trial Services in Israel <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">Launched in 2011, Oximio, Israel, has established a reputation as a reliable provider of high-quality, global, end-to-end supply chain services for clinical trials. With a flexible approach and excellent, long-standing relationship with the Ministry of Health, it is recognised for its agile approach to providing customer solutions.\u00a0 Situated in Caesarea, it benefits from excellent transport links and its own fleet of vehicles enabling quick access to hospitals. Its comprehensive services provide a start to finish solution for clinical trials logistics.\u00a0\u00a0 <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-85e6fae elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"85e6fae\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Israel Local Depot<\/h3><p><strong>Certification:<\/strong><\/p><ul style=\"list-style-type: disc; padding-bottom: 1em; padding-left: 1em;\"><li><span data-contrast=\"auto\">GMP License<\/span><\/li><li><span data-contrast=\"auto\">GDP License<\/span><\/li><li><span data-contrast=\"auto\">MIA License<\/span><\/li><li><span data-contrast=\"auto\">ISO9001:2015 Certification<\/span><\/li><\/ul><p><strong>Product Types:<\/strong><\/p><ul style=\"list-style-type: disc; padding-bottom: 1em; padding-left: 1em;\"><li><span data-contrast=\"auto\">Controlled Drug (CD)\u00a0<\/span><\/li><li><span data-contrast=\"auto\">Dangerous Goods (DG)<\/span><\/li><li><span data-contrast=\"auto\">Biological Goods<\/span><\/li><li><span data-contrast=\"auto\">Blood Product or Derivative<\/span><\/li><li><span data-contrast=\"auto\">Genetically Modified Organism (GMO)<\/span><\/li><li><span data-contrast=\"auto\">Antibiotic<\/span><\/li><li><span data-contrast=\"auto\">Cytotoxic<\/span><\/li><\/ul><p><strong>Storage Conditions:<\/strong><\/p><ul style=\"list-style-type: disc; padding-bottom: 1em; padding-left: 1em;\"><li><span data-contrast=\"auto\">Overall storage capacity 1312 m2<\/span><\/li><li><span data-contrast=\"auto\">Uncontrolled ambient<\/span><\/li><li><span data-contrast=\"auto\">Controlled ambient: +15\u00b0C to +25\u00b0C<\/span><\/li><li><span data-contrast=\"auto\">Refrigerated: +2\u00b0C to +8\u00b0C<\/span><\/li><li><span data-contrast=\"auto\">Frozen: -25\u00b0C to -15\u00b0C<\/span><\/li><li><span data-contrast=\"auto\">Ultra-low: -80\u00b0C to -60\u00b0C<\/span><\/li><li><span data-contrast=\"auto\">Liquid nitrogen (LN2) on request<\/span><\/li><\/ul><p><strong>QP Documents for IMPs:<\/strong><\/p><ul style=\"list-style-type: disc; padding-bottom: 1em; padding-left: 1em;\"><li><span data-contrast=\"auto\">Invoice<\/span><\/li><li><span data-contrast=\"auto\">Shipping documents: Packing list, AWB<\/span><\/li><li><span data-contrast=\"auto\">Temperature (if applicable \u2013 humidity) monitoring results during shipment<\/span><\/li><li><span data-contrast=\"auto\">Label proofs: primary and secondary<\/span><\/li><li><span data-contrast=\"auto\">Form 7<\/span><\/li><li><span data-contrast=\"auto\">CoA from manufacturing site\u00a0<\/span><\/li><li><span data-contrast=\"auto\">Authorized person statement of release\u00a0<\/span><\/li><li><span data-contrast=\"auto\">GMP compliance certificates of all manufacturing chain facilities, inc. product manufacturing, testing, labelling and packaging<\/span><\/li><li><span data-contrast=\"auto\">Pedigree documentation \u2013 all involved in the manufacturing chain: manufacturing, testing,\u00a0<\/span>packaging and labelling, storage must be included<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li><li><span data-contrast=\"auto\">Declaration stating if a product contains\/ does not contain ingredients originated from human blood or plasms<\/span><\/li><li><span data-contrast=\"auto\">Lot linking documents in case of kit, linking the kit lot number and the lot number of product\/s inside<\/span><\/li><li><span data-contrast=\"auto\">Confirmation on the product cytotoxicity<\/span><\/li><li><span data-contrast=\"auto\">Label proofs for all IMPs<\/span><\/li><li><span data-contrast=\"auto\">Clinical Trial Instruction (CTI)<\/span><\/li><li><span data-contrast=\"auto\">Site list<\/span><\/li><li><span data-contrast=\"auto\">Logistics documents: Temperature monitor instruction sheet, Request for order to site, Request\u00a0<\/span>for collection of return forms site to depot, Request for destruction\u00a0<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li><li><span data-contrast=\"auto\">Codes for IRT system (if applicable)<\/span><\/li><\/ul><p><strong>List of documents required for clinical trial start-up:<\/strong><\/p><ul style=\"list-style-type: disc; padding-bottom: 1em; padding-left: 1em;\"><li><span data-contrast=\"auto\">MSA between parties<\/span><\/li><li><span data-contrast=\"auto\">Quality Agreement (Applicable when import of medicinal products is included in the scope of\u00a0<\/span>services)<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li><li><span data-contrast=\"auto\">Copy of Study approval issued by the Ministry of Health (MoH) Form 7 (site specific form):\u00a0<\/span>one form 7 is required for IL application. A site-specific form 7 is required before dispatch to sites.<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li><\/ul><h2><span data-contrast=\"auto\">Contact Oximio\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">If you need support with logistics for clinical trials in Israel, please <span style=\"text-decoration: underline;\"><a href=\"https:\/\/oximio.com\/contact\/\">contact us<\/a><\/span> to find out how our flexible, end-to-end clinical trial services can be tailored to suit your requirements.\u00a0<\/span><\/p><p><strong>References:\u00a0<\/strong><\/p><p><span data-contrast=\"auto\">(1)<\/span>\u00a0<span style=\"text-decoration: underline;\"><a href=\"https:\/\/tracxn.com\/explore\/AI-in-Healthcare-Startups-in-Israel\">https:\/\/tracxn.com\/explore\/AI-in-Healthcare-Startups-in-Israel<\/a><\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":2853,"template":"","meta":{"_acf_changed":false},"resources-categories":[6],"class_list":["post-2852","oximio-resources","type-oximio-resources","status-publish","has-post-thumbnail","hentry","resources-categories-insights"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Clinical Trial Services Israel | Innovation | Latest Insights<\/title>\n<meta name=\"description\" content=\"In this Insight we explore the latest Innovations &amp; Opportunities for Clinical Trials within Israel. 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